Other Names: N-Acetyl-5-methoxytryptamine, N-[2-(5-methoxy-1H-indol-3-yl)ethyl].

What it is: Naturally secreted by the pineal gland, this hormone regulates the sleep-wake cycle in humans. The synthetic form is used in hair growth serums to reduce stress-induced hair fall and male & female pattern hair fall.

Mode of usage pertaining to the discussion below: Topical application in cosmetics and personal care products.

Safety Profile (Based on regional guidelines):

Safety in special situations:

Safe to use, as per current practice

Not listed as an ingredient to be avoided by nursing mothers based on currently available data

Not listed as an ingredient to be avoided in baby products based on currently available data

Not listed as an ingredient to be avoided by children based on currently available data

Not listed as an ingredient to be carcinogenic or mutagenic based on currently available data

Environmental and Ecological Concerns:

Note:

• You may need to look at the exact product claim to know if a vegan version was used.
• You may need to look at the exact product label to know if a naturally derived ingredient was used.

Attributes:

Conclusion
Melatonin is safe as per the current practice of use. In pregnancy, the use of melatonin is best guided by your treating physician.

References

1. https://ec.europa.eu
2. https://www.fda.gov
3. https://pubchem.ncbi.nlm.nih.gov
4. https://european-union.europa.eu
5. https://pubmed.ncbi.nlm.nih.gov

Disclaimer: The above information is based on ongoing toxicology research at CHOSEN®’s R&D. We will do our best to update the information as and when the latest studies are available. If you have any inputs regarding the above information, please email us at ingredients@chosenstore.in