When it comes to antiaging skincare, peptides for skin have taken centre stage, and one peptide, in particular, is stealing the spotlight—Epidermal Growth Factor (EGF). But why is there so much buzz around EGF? And is it truly better than skincare staples like retinol or vitamin C? Let’s break it down!

What is EGF?

EGF or Epidermal Growth Factor, is a peptide chain made up of specific amino acids. Your body naturally produces EGF, and it’s present in blood plasma, platelets, saliva, and even tears.

Did you know that PRP (Platelet-Rich Plasma) therapy, a popular treatment for hair loss and skin rejuvenation, works partly because of these growth factors? 

Beyond aesthetics, EGFs have been used in medicine for years—from preventing post-radiation burns in oncology to healing ulcers in gastroenterology.

Now, the skincare world is embracing EGF based peptide serums and creams for their skin-repairing and anti-aging benefits, offering a gentler alternative to retinol or vitamin C for those with sensitive skin.

How does EGF work on your skin?

Think of Epidermal Growth Factor Receptors (EGFR) on your skin as locks, and EGF as the key. When applied topically through an EGF based peptide serum or cream, these growth factors bind to the receptors on your skin’s surface. This triggers cell renewal, repair, and regeneration, leading to faster skin healing and regeneration of your skin.

In short, EGF is your skin’s natural reset button—helping it heal, repair, and look more youthful!

What are the products at CHOSEN with EGFs?

At CHOSEN, we’ve curated two best EGF-powered skincare products to help you unlock healthier skin:

1. Peptide Therapy Intense Repair Gel

If you have oily, combination, or acne-prone skin, this EGF based peptide skin serum is perfect for you! It contains Sh-Oligopeptide-1, a bioengineered recombinant EGF, known for its powerful skin-repairing properties.

Benefits of Peptide Therapy Gel for your skin:

• Promotes faster healing after procedures like lasers and chemical peels

• Controls acne breakouts—studies show a 33.5% reduction in inflammatory acne in just 6 weeks!

• Aids in acne scar reduction as a monotherapy or in combination with treatments like fractional CO₂ lasers

• Minimizes fine lines and wrinkles

• Reduces hyperpigmentation (including melasma)

• Rejuvenates the undereye area.

How to Use: Apply 1 to 2 pumps, once or twice daily for up to 12 weeks for the best results.

2. Peptide Therapy Intense Repair Crème

If your skin is dry, flaky, or in need of deep hydration, this EGF-infused face moisturizer is a game changer! It combines Sh-Oligopeptide-1 with Hyaluronic Acid, Kalahari Melon Seed Oil, Meadowfoam Seed Oil, and Plant Squalane for multi-functional skin benefits.

Benefits of Peptide Therapy Intense Repair Crème

• Deep hydration and improved skin barrier function

• Faster healing post-clinical treatments

• Prevents premature aging—reducing fine lines and wrinkles

• Protects against photoaging

• Lifting and firming effect

• Brightens and rejuvenates the undereye area

How to Use: Apply the required amount of the product once or twice daily for up to 12 weeks for visible results.

A quick cheat sheet for you to choose the best EGF product for your skin: